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KMID : 1044320190210020113
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Annals of Clinical Neurophysiology
2019 Volume.21 No. 2 p.113 ~ p.116
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Uncommon coexistence of myasthenia gravis and amyotrophic lateral sclerosis
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Cho Eun-Bin
Yang Tae-Won
Jeong Hee-Jeong
Yoon Chang-Hyo
Jung Seung-Uk
Park Ki-Jong
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Abstract
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Myasthenia gravis (MG) and amyotrophic lateral sclerosis (ALS) are distinct disorders. ALS affects motor neurons that control muscle movement, while MG controls communication between neurons and muscles, which occurs at neuromuscular junctions. However, on rare occasions, ALS develops after MG and vice versa. The coexistence of the two diseases represents a diagnostic challenge and requires thoughtful interpretation of clinical features. We present the case of a 53-year-old Korean male who developed ALS after MG, confirmed by clinical and electrophysiological follow-up.
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KEYWORD
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Myasthenia gravis, Amyotrophic lateral sclerosis, Overlap
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